![]() Most of the studies that estimate the prevalence of burnout focused on different occupational group primarily service-related professions with rates ranging from 25 to 60%. Originally, the burnout symptoms were found to occur only in client-related occupations, but now include all types of work. Burnout in workplaces has been attributed to different factors, which can be classified as organizational and individual factors and occurs in workers as a result of failure to cope with occupational stress. It is an outcome of chronic depletion of the individual’s coping resources resulting from prolonged exposure to stress, particularly work-related stress. The most widely used Maslach Burnout Inventory (MBI) measures burnout across the three dimensions, emotional exhaustion (EE), personal accomplishment (PA) and depersonalization (DP). The professional burnout is a psychological syndrome occurring in response to chronic job stress. Our findings demonstrated the interest of sleep and biological parameters, in particular HbA1C levels, in the characterization of professional burnout. However, when HbA1C levels is included, the prediction of burnout became significant (P = 0.03). Models including job strain, job satisfaction, anxiety and insomnia did not predict burnout (p = 0.30 and p = 0.50). Strong significant positive correlation existed between HbA1C and the two dimensions (emotional exhaustion and depersonalization (r = 0.79 and r = 0.71, p<0.01)) of burnout. Besides reporting more job strain (in particular job control p = 0.02), higher levels of anxiety (p 3.5%, the prevalence of burnout increases from 16.6% to 60.0% (OR = 4.3, 95%CI = 2.8–6.9). Analysis of variance and a forward Stepwise Multiple Logistic Regression were made to identify predictive factors of burnout. Fasting concentrations of glycaemia, glycosylated hemoglobin (HbA1C), total-cholesterol, triglycerides, C-reactive protein (CRP), thyroid stimulating hormone (TSH), 25-hydroxyvitamin D (25D), and white blood cell (WBC) counts were assessed. ![]() Fifty-four participants with burnout were compared to 86 healthy control participants in terms of professional rank level, sleep, job strain (Karasek questionnaire), social support, anxiety and depression (HAD scale). We investigated the interest of exploring biological parameters and sleep disturbances in relation to burnout symptoms among white-collar workers. Professional burnout syndrome has been described in association with insomnia and metabolic, inflammatory and immune correlates.
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